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Silvia Pezzola Selected Research

6- (7- nitro- 2,1,3- benzoxadiazol- 4- ylthio)hexanol

9/2009In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma.
7/2009The glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol overcomes the MDR1-P-glycoprotein and MRP1-mediated multidrug resistance in acute myeloid leukemia cells.
2/20086-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1-mediated MDR in small cell lung cancer.

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Silvia Pezzola Research Topics

Disease

5Neoplasms (Cancer)
10/2017 - 02/2008
1Alzheimer Disease (Alzheimer's Disease)
01/2014
1Osteosarcoma (Osteogenic Sarcoma)
04/2012
1Necrosis
04/2012
1Breast Neoplasms (Breast Cancer)
01/2010
1Melanoma (Melanoma, Malignant)
09/2009
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
07/2009
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
02/2008

Drug/Important Bio-Agent (IBA)

3Glutathione Transferase (Glutathione S-Transferase)IBA
01/2015 - 02/2008
36- (7- nitro- 2,1,3- benzoxadiazol- 4- ylthio)hexanolIBA
09/2009 - 02/2008
2Cisplatin (Platino)FDA LinkGeneric
10/2017 - 04/2012
2Pharmaceutical PreparationsIBA
04/2012 - 07/2009
2multidrug resistance-associated protein 1IBA
07/2009 - 02/2008
2Proteins (Proteins, Gene)FDA Link
07/2009 - 02/2008
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
10/2017
1CamptothecinIBA
10/2017
1Antineoplastic Agents (Antineoplastics)IBA
10/2017
1Amyloid (Amyloid Fibrils)IBA
01/2014
1Peptides (Polypeptides)IBA
01/2014
1Glutathione S-Transferase piIBA
04/2012
1CaspasesIBA
04/2012
1IsoenzymesIBA
01/2010
1brostallicinIBA
01/2010
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
02/2008
1Adenosine Triphosphate (ATP)IBA
02/2008

Therapy/Procedure

1Therapeutics
09/2009